2,4,6-Triisopropylbenzenesulfonyl chloride 2,4,6-三异丙基苯磺酰氯

规格: 98%
CAS: 6553-96-4
产品编号: H77403
MDL: MFCD00007433
品牌: INFI
Chemical Name2,4,6-triisopropylbenzene-1-sulfonyl chloride
MDL NumberMFCD00007433
CAS Number6553-96-4
EC Number229-479-6
Beilstein Registry Number1218575
Synonym 2,4,6-TRIISOPROPYLBENZENESULPHONYL CHLORIDE 2,4,6-Triisopropylbenzene-1-sulfonyl chloride {Chemicalbook} 2,4,6-Tris(1-methylethyl)benzenesulfonyl chloride 2,4,6-三异丙基苯磺酰氯 2,4,6-三异丙基苯磺酸氯 Benzenesulfonyl chloride, 2,4,6-tris(1-methylethyl)- TRI ARYL SULFONIUM CHLORIDE Trisyl chloride {} {Chemicalbook} 2,4,6-Triisopropylbenzenesulfonic acid chloride
PubChem Substance ID81042
Chemical Name Translation2,4,6-三异丙基苯磺酰氯
Reaxys-RN1218575
InChIKeyJAPYIBBSTJFDAK-UHFFFAOYSA-N
LabNetwork Molecule IDLN00170489
InChIInChI=1S/C15H23ClO2S/c1-9(2)12-7-13(10(3)4)15(19(16,17)18)14(8-12)11(5)6/h7-11H,1-6H3
Canonical SMILESO=S(C1=C(C(C)C)C=C(C(C)C)C=C1C(C)C)(Cl)=O
GHS Symbol
Signal word Danger
WGK Germany3
Safety Statements
  • S20 When using do not eat or drink 使用时，不得进食，饮水；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
    Risk Statements
    • R29 Contact with water liberates toxic gas. 遇水释放出有毒气体
    • R34 Causes burns 会导致灼伤
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P234 Keep only in original container. 只保留在原来的容器中。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P330+P331
      • P303+P361+P353+P310+P363
      • P304+P340+P310
      • P305+P351+P338
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Packing GroupII
        UN Number 3261 UN 3261 8/PG 2 UN3096
        Storage condition 0-10 0-10°C 2-8°C Moisture Sensitive Store at RT. 易吸潮, 阴凉干燥处保存。
        Hazard statements
        • H290 May be corrosive to metals 可能腐蚀金属。
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
          Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
          Hazard Codes 8 C
          Hazard Class8
        • {ALF} Hindered sulfonyl chlorides have found use as condensing agents for the formation of the phosphate link of oligonucleotides. For reviews, see: Angew. Chem. Int. Ed., 11, 451 (1972); Synthesis, 222 (1975); Chem. Rev., 77, 183 (1977). For reviews of oligonucleotide synthesis by the phosphotriester method, see: Heterocycles, 7, 1197 (1977); Tetrahedron, 34, 3143 (1978). For use as a condensing agent in the synthesis of H-phosphonate diesters, see: Nucleosides Nucleotides, 7, 23 (1988). More hindered in comparison with, e.g. Mesityl­ene-2-sulfonyl­ chloride, A11775, and so has less tendency to react with the free 5'-hydroxyl group of sugars: J. Am. Chem. Soc., 88, 829 (1966).
        • {ALD} Beilstein: 11,III,365
        • {ALF} For examples of the utility of the triisopropylbenzenesulfonyl group in the protection of OH groups, see: J. Am. Chem. Soc., 117, 5693, 5776 (1995): (first synthesis of a digitalis saponin and asymmetric synthesis of (-) and (+)-strychnine, respectively).
          • 6553-96-4 H77403 2,4,6-Triisopropylbenzenesulfonyl chloride 2,4,6-三异丙基苯磺酰氯

          化学属性

          Mol. FormulaC15H23ClO2S
          Mol. Weight302.86
          Density1.096
          Melting Point94-97°C
          TSCANo
          Solubility分解
          Stability易吸潮
          Boiling Point349.3°C at 760 mmHg
          Flash Point165.1°C