Methyl phenyl sulfide 甲基苯基硫醚

规格: 99%
CAS: 100-68-5
产品编号: H89700
MDL: MFCD00008559
品牌: INFI
Chemical NameMethyl phenyl sulfide
MDL NumberMFCD00008559
CAS Number100-68-5
EC Number202-878-2
Beilstein Registry Number1904179
Synonym (1-Thiaethyl)benzene (Methylsulfanyl)benzene (methylthio)benzene 1-Phenyl-1-thioethan 1-phenyl-1-thiaethane Anisole, thio- FEMA 3873 MPS Methyl phenyl sulfi Methyl phenyl sulfide, Methylthiobenzene Methyl phenyl sulfide; MPS Methyl phenyl thioether Methyl phenylsulfide Methylphenylsulfid PHSME Phenyl methyl sulfide Phenylthiomethane Sulfide, methyl phenyl Thioanisol benzene, (methylthio)- methyl phenyl sulfide methyl phenyl thioether methyl-phenyl sulfide methylphenylthioether sulfide,methylphenyl thioanisole 甲基苯基硫醚 甲基苯基硫醚 茴香硫醚 苯基甲基硫醚 苯甲硫醚 茴香硫醚
PubChem Substance ID87576182
Reaxys-RN1904179
Chemical Name Translation甲基苯基硫醚
Wiswesser Line Notation1SR
LabNetwork Molecule IDLN00221864
InChIInChI=1S/C7H8S/c1-8-7-5-3-2-4-6-7/h2-6H,1H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00184

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 891 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCBPBS Pesticide Biochemistry and Physiology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1971-  Volume(issue)/page/year:
   1,356,1971

Signal word Warning
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
    Risk Statements
    • R22 Harmful if swallowed 吞咽有害
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P233 Keep container tightly closed. ?保持容器密闭。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P241+P242+P243
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P312+P330
      • P302+P352+P332+P313+P362+P364
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P332+P313
      • P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P370+P378
      • P403+P235
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
        • H302 Harmful if swallowed 吞食有害
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H226 Flammable liquid and vapour 易燃液体和蒸气
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          RTECSDA6200000
          Packing GroupIII
          UN Number 1993 3334
          Hazard Codes 3 9
          Hazard Class3
          Storage condition 2-8°C
        • 高效启动剂,用于酸催化裂解N-Z, O-benzyl 和 O-methyl保护基团。
        • {ALD} Beilstein:6,297
        • {uni_hamburg} Short: II/24C
        • {ALF} Cation scavenger in the acidic deprotection of peptides; see, e.g.: Int. J. Pept. Prot. Res., 36, 255 (1990). See Appendix 6. The combination of the soft nucleophile thioanisole and the hard acid triflic acid has been used for the cleavage of methyl ethers, e.g. O-methyltyrosine, resistant to other methods: J. Chem. Soc., Chem. Commun., 971 (1979). The same conditions have been used for the cleavage of Cbz, Boc, benzyl and 4-methoxybenzyl protecting groups in peptide synthesis: Chem. Pharm. Bull., 28, 1214 (1980); 29, 600 (1981); J. Chem. Soc., Chem. Commun., 101 (1980); see also: Angew. Chem. Int. Ed., 33, 1729 (1994).
        • {uni_hamburg} Short: II/24B
        • {ALF} Monolithiation is thought to occur initially on the ring, but rearrangement then gives the more stable phenylthiomethyllithium: J. Org. Chem., 31, 4097 (1966); Tetrahedron Lett., 1961 (1977). Further metallation occurs at the ortho-position. See, e.g.: Tetrahedron, 46, 861 (1990). Demetallation and acylation is the basis of a route to 3-substituted benzo[b]thiophenes: Synthesis, 888 (1988):
        • 100-68-5 H89700 Methyl phenyl sulfide	甲基苯基硫醚

          化学属性

          Mol. FormulaC6H5SCH3
          Mol. Weight124
          Density1.057
          Refractive index1.5860 to 1.5880
          Boiling Point188
          Melting Point-15
          Flash Point57°C(lit.)
          TSCAYes
          Solubility不溶
          Appearance 无色液体,沸点187-188oC,相对密度1.0533,闪点75oC,折射率1.5842。不溶于水,可溶于一般有机溶剂。
          Stability恶臭