Iodine, solution 0,5 mol/l (1 N) 碘溶液,0,5 mol/l (1 N)

规格: solution 0,5 mol/l (1 N)
CAS: 7553-56-2
产品编号: YO00241000
MDL: MFCD00011355
品牌: Scharlab
Chemical NameIodine
CAS Number7553-56-2
EC Number231-442-4
Beilstein Registry Number3587194
MDL NumberMFCD00011355
Reaxys-RN3587194
PubChem Substance ID807
Merck Number5014
Synonym Actomar Diatomic iodine Eranol I (iodine) I2 (iodine) IODE Iod-Iodid Iodine Iodine (127I2) Iodine (Iodine-Iodide) Iodine 127 Iodine colloidal Iodine concentrate Iodine crystals Iodine molecule (I2) Iodine sublimed Iodine, chips Iodine-127 Iodio Iosan Superdip Jod Jodosan Jood Tincture iodine Vistarin diiodine molecular iodine molekulares Iod {} {uni_hamburg} 碘 碘 (I2) 0.25mol 碘 溶液 碘(药用),碘片 碘容量分析用溶液标准物质 精碘,碘片 精碘;碘片
Chemical Name TranslationIodine
Wiswesser Line NotationI2
LabNetwork Molecule IDLN00221523
InChIInChI=1S/I2/c1-2
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOS

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,876,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >8650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,1226,1990

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 26 mg/kg/1Y-I
TOXIC EFFECTS :
   Endocrine - evidence of thyroid hyperfunction
REFERENCE :
   PGMJAO Postgraduate Medical Journal.  (Blackwell Scientific Pub. Ltd., POB
   88, Oxford, UK) V.1-    1925-  Volume(issue)/page/year: 62,661,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/

TYPE OF

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2750 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   JONUAI Journal of Nutrition.  (Subscription Dept., 9650 Rockville Pike,
   Bethesda, MD 20014) V.1-    1928-  Volume(issue)/page/year: 84,107,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1100 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
REFERENCE :
   JONUAI Journal of Nutrition.  (Subscription Dept., 9650 Rockville Pike,
   Bethesda, MD 20014) V.1-    1928-  Volume(issue)/page/year: 84,107,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 15 mg/kg
SEX/DURATION            : female 30-31 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   JONUAI Journal of Nutrition.  (Subscription Dept., 9650 Rockville Pike,
   Bethesda, MD 20014) V.1-    1928-  Volume(issue)/page/year: 87,394,1965

WGK Germany2
Hazard Codes 8 Xn;N
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H312+H332
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
    Personal Protective Equipment Faceshields, Gloves, Goggles Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Faceshields, Gloves Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSNN1575000
    Precautionary statements
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
    • P301+P312
    • P302+P352
    • P303+P361+P353
    • P304+P312
    • P304+P340
    • P305+P351+P338
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
    • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
    • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
    • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
    • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
    • P330 Rinse mouth. 漱口
    • P332+P313
    • P333+P313
    • P337+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403+P233
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger Warning
      UN Number 1759/1760 2923 UN 2056 3/PG 2
      Safety Statements
      • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
      • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
      • S25 Avoid contact with eyes 避免眼睛接触;
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
      • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
        Risk Statements
        • R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害
        • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
        • R50 Very toxic to aquatic organisms 对水生生物极毒
          Packing GroupIII
          Hazard Class8/6.1
          Storage condition Store at RT. 储存温度2-8℃ 密封阴凉避光保存。 密封阴凉避光保存。充氩保存 室温储存 储存温度2-8℃,避光保存。
        • 用于ICP-AES、AAS、AFS、ICP-MS、离子色谱等。滴定分析用标准溶液。
        • {ALFA} Secondary, tertiary or benzylic alcohols can be converted directly to the corresponding iodides by simply refluxing with iodine in petroleum ether: Tetrahedron Lett., 36, 609 (1995).
        • {ALFA} The stereochemistry of the iodolactonization of unsaturated acids to give -lactones can be controlled in some cases. Using I2_-_NaHCO3, the product is under kinetic control, but in acetonitrile, without base, the reaction is reversible and therefore under thermodynamic control. For tabulated results, see: Org. Synth. Coll, 7, 164 (1990):
        • {ALFA} Iodine is also a useful mild oxidant, e.g. of aldehydes to acids in alkaline medium: Tetrahedron Lett., 33, 4329 (1992); in DMSO, stilbenes and diaryl acetylenes give benzils: Synthesis, 131 (1991); with hydrogen peroxide, hydroquinones are oxidized to quinones: J. Org. Chem., 54, 718 (1989).
        • {uni_hamburg} Short: II/24A
        • {ALFA} For use in the functionalization of remote positions (Barton reaction), see Lead(IV)­ acetate, A15551.
        • {ALD} Merck: 14,5014
        • {ALFA} For use in hydroboration and reduction reactions, see Sodium borohydride, 35788.
        • {ALFA} Iodolactamisation of amides can similarly be achieved by prior silylation: J. Org. Chem., 53, 4006 (1988); Org. Synth. Coll., 9, 516 (1998):
        • {ALFA} Efficient catalyst for the formation of 1,1-diacetates from aldehydes and acetic anhydride: J. Org. Chem., 62, 1563 (1997).
        • 7553-56-2 YO00241000 Iodine, solution 0,5 mol/l (1 N) 	碘溶液,0,5 mol/l (1 N)

          化学属性

          Mol. FormulaI{2}
          Mol. Weight254
          Boiling Point185
          Melting Point113
          Density1.034
          TSCAYes
          Flash PointNone
          Vapor Density9 (vs air)
          Vapor Pressure0.31 mmHg ( 25 °C)
          Solubility0.3 G/L (20 ºC)
          Appearance particles (round)
          Stability对光敏感